We have defined our Purpose to express our Reason for Existence and the value we aim to provide to society.
Our Vision articulates what our company should aspire to be in order to realize our Purpose.
And our Value establishes the organizational values and culture that will guide us towards achieving our Purpose and Vision.

Our Purpose

Harnessing the science of extracellular vesicles (EVs)
to deliver new options to people hoping to have children.

Our Vision

To become a leading ART biotechnology company
by integrating EV technology with reproductive medicine
and contributing to improved embryo quality
and the embryo culture environment.

Our Value

  • Value 01
    Patient First

    We always prioritize the interests of patients first and foremost.

  • Value 02
    Evidence Based

    We always conduct evidence-based product development.

  • Value 03
    Challenge

    We take appropriate risks and face challenges boldly,
    while continuing to humbly learn from both successes and failures.

  • Value 04
    Collaborate

    We respect diversity and cooperate with each other to build strong teams.

  • Value 05
    Enjoy

    We enjoy taking on challenges to create a better future.

Message

Pioneering the future of reproductive medicine through extracellular vesicle (EV) technology.

At EXORPHIA, we are committed to creating new options in the field of Assisted Reproductive Technology (ART) by leveraging our research and development platform for extracellular vesicles (EVs).

As the trend toward later childbearing continues and the demand for infertility treatment increases, there is a growing need for new technological approaches to address challenges related to embryo development and embryo quality in IVF. We are developing an acellular EV-containing IVF culture media supplement designed to support the optimization of the ex vivo embryo culture environment, with the goal of contributing to improved IVF outcomes.

For our lead product candidate, we are building on findings from non-clinical studies and collaborating with ART clinics and academic institutions to evaluate its utility as a novel embryo culture technology, including its safety profile and embryo development- and embryo quality-related outcomes. This technology is intended for use in the ex vivo embryo culture process, contains no living cells, and is not administered to patients.

At EXORPHIA, we are focused on advancing scientifically grounded, quality-controlled technologies that can contribute to reproductive medicine. We will concentrate our management resources on the ART business.

June 2026
Koji Kuchishi
President & CEO
EXORPHIA Inc.

Company Profile

Company Name
EXORPHIA, INC.
Business Description
Research, development, manufacturing, and commercialization of EV-based products, including high-performance supplements for in vitro fertilization (IVF).
Location
Head Office and Lab: Inspired.Lab, 6th Floor, Otemachi Building, 1-6-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan
Establishment Date
May 7, 2019
Capital
100 million yen (Accumulated Funds Raised 1,489 million yen)
CEO
Koji Kuchiishi
Academic Research Partners
The University of Tokyo  MIE University
Collaborative Research Representatives
  • Associate Professor NAGAMURA-INOUE Tokiko, M.D., Ph.D., Department of Cell Processing and Transfusion, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo
  • Assistant Professor Hiroki Takeuchi, Ph.D., Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine

History

May 2019
Company established
July 2019
Capital increase through third-party allotment
August 2019
Laboratory opened
December 2019
Capital increase through third-party allotment
January 2020
In-house research ethics review committee established
May 2020
Collaboration with The Institute of Medical Science, The University of Tokyo and Juntendo University initiated
April 2021
Head office and laboratory relocated to Inspired.Lab, 6th Floor, Otemachi Building, Chiyoda-ku, Tokyo
Capital increase through third-party allotment
June 2021
Board of Directors and Audit & Supervisory Board established
April 2022
Capital increase through third-party allotment
July 2023
Raised 325 million yen from KII, Coral Capital, and one other venture capital firm through the issuance of stock acquisition rights
March 2024
Raised 550 million yen from two business companies through the issuance of stock acquisition rights
December 2024
Selected for the NEDO Deep Tech Startup Support Program
December 2024
Received an additional investment of 180 million JPY from Coral Capital
April 2025
Began joint research with Mie University on oocyte maturation technology for in vitro fertilization (IVF)

Leadership team

Board of Directors

Office

〒100-0004
Otemachi Bldg. 6F, 1-6-1 Otemachi, Chiyoda-ku, Tokyo

Access
・Directly connected to Otemachi Station, which is connected to five subway lines.
・Direct access from the underground shopping area in Tokyo Station.